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2019 Lectures
FEB
5
Lunch: 11:45 am
Lecture: 12:15 - 1:15 pm

Hudson Webber Cancer Research Center, Second Floor, Wertz Auditorium
4100 John R. Street, Detroit, MI 48201
A Novel Approach to Rejuvenate Endogenous Treg Function
in the Treatment of Autoimmune Diseases
E. Garrison Fathman, M.D.
Professor of Medicine (Immunology and Rheumatology)
Director, Center for Clinical Immunology
Chief, Division of Immunology and Rheumatology
Stanford University School of Medicine
Host: Harley Tse
Department of Biochemistry, Microbiology and Immunology
Wayne State University
  • IconSpeaker Profile

      Dr. Fathman has been a leading figure in clinical immunology and has made fundamental contributions to the cellular and molecular understanding of T cell function. He has published numerous articles across the world’s top scientific journals, such as Nature, Science, Cell, New England Journal of Medicine, Nature Immunology, Nature Medicine, and Immunity. He has also been in the leadership role of many prestigious international organizations, such as being the founder and the first President of the Federation of Clinical Immunology Societies. His lab recently discovered a novel pathway in Treg IL-2R signaling controlled by GRAIL. By targeting the relevant pathway defect in human autoimmune diseases, his group was able to restore immune regulation and block progression of disease in animal models of autoimmunity. He recently spun a company out of Stanford to develop this therapy.

Garry Fathman
JAN
8
Lunch: 11:45 am
Lecture: 12:15 - 1:15 pm

Hudson Webber Cancer Research Center, Second Floor, Wertz Auditorium
4100 John R. Street, Detroit, MI 48201
Immune Drug Discoveries at Pfizer
Ethan M. Shevach, M.D.
Senior Investigator
Chief, Cellular Immunology Section
National Institute of Allergy and Infectious Diseases
National Institutes of Health
Host: Eric Sebzda
Department of Biochemistry, Microbiology and Immunology
Wayne State University
  • IconSpeaker Profile

      Dr. Ethan Shevach is Head of the Section of Cellular Immunology at NIAID. He has served as the Editor-in-Chief of the Journal of Immunology (1987-1992) and of Cellular Immunology (1996-2007). His groundbreaking research on regulatory T cell biology has garnered him numerous awards including the William B. Coley Award for Distinguished Research in Basic and Tumor Immunology (2004), a Distinguished Service Award (The American Association of Immunologists), and a Distinguished Alumnus Award (Boston University Medical School). Dr. Shevach has published nearly 400 peer-reviewed publications in premier scientific journals and is one of the most highly cited immunologists in the world.

Ethan Shevach