Immunology Focus Group Newsletter
February 2019, Number 1
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IFG Lecture - February 2019
Garry Fathman
Lunch for lecture audience: 11:45 am
Lecture:12:15 - 1:15 pm

Wertz Auditorium (Hudson Webber Cancer Research Center, 2nd floor)
4100 John R., Detroit, MI 48201
Meeting with trainees: 1:30- 2:15 pm

Jointly Hosted by:
Department of Biochemistry, Microbiology and Immunology
Department of Oncology, Barbara Ann Karmanos Cancer Institute
Immunology Focus Group

Supported by:
Barbara Ann Karmanos Cancer Institute
Office of the Vice President for Research, Wayne State University
Henry Ford Health System

A Novel Approach to Rejuvenate Endogenous Treg Function
in the Treatment of Autoimmune Diseases

C. Garrison Fathman, M.D.
Professor of Medicine (Immunology and Rheumatology)
Director, Center for Clinical Immunology
Chief, Division of Immunology and Rheumatology
Stanford University School of Medicine

Hosts: Harley Tse, PhD
Department of Biochemistry, Microbiology and Immunology, Wayne State University
Dr. Fathman has been a leading figure in clinical immunology and has made fundamental contributions to the cellular and molecular understanding of T cell function. He has published numerous articles across the world’s top scientific journals, such as Nature, Science, Cell, New England Journal of Medicine, Nature Immunology, Nature Medicine, and Immunity. He has also been in the leadership role of many prestigious international organizations, such as being the founder and the first President of the Federation of Clinical Immunology Societies. His lab recently discovered a novel pathway in Treg IL-2R signaling controlled by GRAIL. By targeting the relevant pathway defect in human autoimmune diseases, his group was able to restore immune regulation and block progression of disease in animal models of autoimmunity. He recently spun a company out of Stanford to develop this therapy.

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